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Upregulation of cytochromes P450 2B in rat liver by orphenadrine
1. The alkylamine drug orphenadrine (ORPH) is an inducer and inhibitor of the microsomal cytochrome P450 (CYP) system in mammals. This study evaluated the selectivity of CYP induction by ORPH in rat liver. 2. Immunoblot analysis indicated that ORPH was a selective inducer of the phenobarbitone (PB)-...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573901/ https://ncbi.nlm.nih.gov/pubmed/12813002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705305 |
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