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Effects of G-protein-specific antibodies and Gβγ subunits on the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells

1. The effects on the whole-cell carbachol-induced muscarinic cationic current (mIcat) of antibodies against the α-subunits of various G proteins, as well as the effect of a Gβγ subunit, were studied in single guinea-pig ileal smooth muscle cells voltage-clamped at −50 mV. Ionized intracellular calc...

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Detalhes bibliográficos
Main Authors: Yan, H -D, Okamoto, H, Unno, T, Tsytsyura, Ya D, Prestwich, S A, Komori, S, Zholos, A V, Bolton, T B
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573886/
https://ncbi.nlm.nih.gov/pubmed/12788820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705289
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