Phospholipase C, but not InsP(3) or DAG, -dependent activation of the muscarinic receptor-operated cation current in guinea-pig ileal smooth muscle cells

1. In visceral smooth muscles, both M(2) and M(3) muscarinic receptor subtypes are found, and produce two major metabolic effects: adenylyl cyclase inhibition and PLCβ activation. Thus, we studied their relevance for muscarinic cationic current (mI(CAT)) generation, which underlies cholinergic excit...

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Detalhes bibliográficos
Main Authors: Zholos, Alexander V, Tsytsyura, Yaroslav D, Gordienko, Dmitri V, Tsvilovskyy, Vladimir V, Bolton, Tom B
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1574170/
https://ncbi.nlm.nih.gov/pubmed/14662735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705584
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