PPAR-α and -γ but not -δ agonists inhibit airway inflammation in a murine model of asthma: in vitro evidence for an NF-κB-independent effect

1. Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that have been proposed to regulate inflammation by antagonising the nuclear factor-κB (NF-κB) signalling pathway. We investigated the role of PPARs using synthetic agonists in murine models of airway i...

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Bibliografiska uppgifter
Huvudupphovsmän: Trifilieff, Alexandre, Bench, Anne, Hanley, Marcus, Bayley, Debbie, Campbell, Emma, Whittaker, Paul
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
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Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573830/
https://ncbi.nlm.nih.gov/pubmed/12746235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705232
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