Evidence for cross-talk between M(2) and M(3) muscarinic acetylcholine receptors in the regulation of second messenger and extracellular signal-regulated kinase signalling pathways in Chinese hamster ovary cells

1. We have examined possible mechanisms of cross-talk between the G(q/11)-linked M(3) muscarinic acetylcholine (mACh) receptor and the G(i/o)-linked M(2) mACh receptor by stable receptor coexpression in Chinese hamster ovary (CHO) cells. A number of second messenger (cyclic AMP, Ins(1,4,5)P(3)) and...

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Detalhes bibliográficos
Main Authors: Hornigold, David C, Mistry, Rajendra, Raymond, Pamela D, Blank, Jonathan L, John Challiss, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573780/
https://ncbi.nlm.nih.gov/pubmed/12711635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705178
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