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Inhibition of G protein-activated inwardly rectifying K(+) channels by fluoxetine (Prozac)
1. The effects of fluoxetine, a commonly used antidepressant drug, on G protein-activated inwardly rectifying K(+) channels (GIRK, Kir3) were investigated using Xenopus oocyte expression assays. 2. In oocytes injected with mRNAs for GIRK1/GIRK2, GIRK2 or GIRK1/GIRK4 subunits, fluoxetine reversibly r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573762/ https://ncbi.nlm.nih.gov/pubmed/12684268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705172 |
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