Activation of a glycine transporter on spinal cord neurons causes enhanced glutamate release in a mouse model of amyotrophic lateral sclerosis

The release of [(3)H]D-aspartate ([(3)H]D-ASP) or [(3)H]GABA evoked by glycine from spinal cord synaptosomes was compared in mice expressing mutant human SOD1 with a Gly(93) Ala substitution ([SOD1-G93A(+)]), a transgenic model of amyotrophic lateral sclerosis, and in control mice. Mice expressing m...

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Bibliografiske detaljer
Main Authors: Raiteri, Luca, Paolucci, Egle, Prisco, Simona, Raiteri, Maurizio, Bonanno, Giambattista
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Special Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573752/
https://ncbi.nlm.nih.gov/pubmed/12684256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705142
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