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Neurogenic responses mediated by vanilloid receptor-1 (TRPV1) are blocked by the high affinity antagonist, iodo-resiniferatoxin

1. Stimulation of the vanilloid receptor-1 (TRPV1) results in the activation of nociceptive and neurogenic inflammatory responses. Poor specificity and potency of TRPV1 antagonists has, however, limited the clarification of the physiological role of TRPV1. 2. Recently, iodo-resiniferatoxin (I-RTX) h...

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Bibliografiska uppgifter
Huvudupphovsmän: Rigoni, Michela, Trevisani, Marcello, Gazzieri, David, Nadaletto, Riccardo, Tognetto, Michele, Creminon, Christophe, Davis, John B, Campi, Barbara, Amadesi, Silvia, Geppetti, Pierangelo, Harrison, Selena
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573721/
https://ncbi.nlm.nih.gov/pubmed/12642400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705110
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