Neurogenic responses mediated by vanilloid receptor-1 (TRPV1) are blocked by the high affinity antagonist, iodo-resiniferatoxin

1. Stimulation of the vanilloid receptor-1 (TRPV1) results in the activation of nociceptive and neurogenic inflammatory responses. Poor specificity and potency of TRPV1 antagonists has, however, limited the clarification of the physiological role of TRPV1. 2. Recently, iodo-resiniferatoxin (I-RTX) h...

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Detalhes bibliográficos
Main Authors: Rigoni, Michela, Trevisani, Marcello, Gazzieri, David, Nadaletto, Riccardo, Tognetto, Michele, Creminon, Christophe, Davis, John B, Campi, Barbara, Amadesi, Silvia, Geppetti, Pierangelo, Harrison, Selena
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573721/
https://ncbi.nlm.nih.gov/pubmed/12642400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705110
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