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Effects of acetaminophen on constitutive and inducible prostanoid biosynthesis in human blood cells

1. Acetaminophen, an analgesic and antipyretic drug with weak antiinflammatory properties, has been suggested to act as a tissue-selective inhibitor of prostaglandin H synthases (PGHSs) (e.g. COX-1 and COX-2) through its reducing activity, that is influenced by the different cellular levels of perox...

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Detalhes bibliográficos
Main Authors: Sciulli, Maria G, Seta, Francesca, Tacconelli, Stefania, Capone, Marta L, Ricciotti, Emanuela, Pistritto, Giuseppa, Patrignani, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573695/
https://ncbi.nlm.nih.gov/pubmed/12598417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705078
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