Alprostadil suppresses angiogenesis in vitro and in vivo in the murine Matrigel plug assay

1. Prostaglandin E(1) (PGE(1), alprostadil) is used as a vasodilator for the treatment of peripheral vascular diseases. 2. Previous reports suggested a pro-angiogenic effect for PGE(1). 3. We studied the in vitro and in vivo effect of PGE(1), complexed with α-cyclodextrin, on the angiogenic process....

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Bibliographic Details
Main Authors: Cattaneo, Maria Grazia, Pola, Sandra, Dehò, Valeria, Sanguini, Anna Maria, Vicentini, Lucia Maria
Format: Artigo
Language:Inglês
Published: 2003
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573673/
https://ncbi.nlm.nih.gov/pubmed/12540529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705051
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