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Greater inotropic and cyclic AMP responses evoked by noradrenaline through Arg389 β(1)-adrenoceptors versus Gly389 β(1)-adrenoceptors in isolated human atrial myocardium
1. We studied the biochemical and contractile responses of isolated human myocardial tissue expressing native receptor variants of the 389G>R β(1)-adrenoceptor polymorphism. 2. Right atrial appendage was obtained from homozygous RR patients (n=37) and homozygous GG patients (n=17) undergoing elec...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573660/ https://ncbi.nlm.nih.gov/pubmed/12540530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705030 |
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