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ADP stimulation of inositol phosphates in hepatocytes: role of conversion to ATP and stimulation of P2Y(2) receptors

1. Accumulation of inositol (poly)phosphates (InsP(x)) has been studied in rat hepatocytes labelled with [(3)H]inositol. Stimulation with ADP resulted in a significant increase in total [(3)H]InsP(x), whereas 2-MeSADP had only a small effect and ADPβS was ineffective. UTP and ITP also stimulated sub...

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Bibliografiske detaljer
Main Authors: Dixon, C Jane, Hall, John F, Boarder, Michael R
Format: Artigo
Sprog:Inglês
Udgivet: 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573642/
https://ncbi.nlm.nih.gov/pubmed/12522099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705016
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