Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension

1. Chronic hypoxic treatment of rats (to induce pulmonary hypertension, PHT) for 14 days increased cGMP-inhibited cAMP specific phosphodiesterase (PDE3) and cGMP binding cGMP specific phosphodiesterase (PDE5) activities in pulmonary arteries. The objective of this study was to establish the molecula...

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Bibliographic Details
Main Authors: Murray, Fiona, MacLean, Margaret R, Pyne, Nigel J
Format: Artigo
Language:Inglês
Published: 2002
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573609/
https://ncbi.nlm.nih.gov/pubmed/12466227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704984
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