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Effects of the selective inhibition of platelet thromboxane synthesis on the platelet-subendothelium interaction

1. Drugs that inhibit TxA(2) synthesis are used to reduce platelet aggregation. The aim of this study was to compare the effects of a cyclo-oxygenase (COX) inhibitor (acetylsalicylic acid, ASA), a thromboxane synthetase (TxS) inhibitor (dazoxiben) and a dual TxS inhibitor and TxA(2) receptor blocker...

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Bibliographic Details
Main Authors: De La Cruz, J P, Villalobos, M A, Escalante, R, Guerrero, A, Arrebola, M M, Sánchez de la Cuesta, F
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573583/
https://ncbi.nlm.nih.gov/pubmed/12429581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704963
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