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Differential coupling of 5-HT(1) receptors to G proteins of the G(i) family

1. Since all 5-HT(1) receptors couple to G(i)–type G proteins and inhibit adenylyl cyclase, the functional significance of five distinct subtypes of 5-HT(1) receptors has been unclear. 2. In previous studies we have used transfected cells to demonstrate that 5-HT(1B) receptors can couple more effici...

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Detalhes bibliográficos
Main Authors: Lin, Stanley L, Setya, Shilpy, Johnson-Farley, Nadine N, Cowen, Daniel S
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573437/
https://ncbi.nlm.nih.gov/pubmed/12145108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704809
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