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Substitution of 5-HT(1A) Receptor Signaling by a Light-activated G Protein-coupled Receptor

Understanding serotonergic (5-HT) signaling is critical for understanding human physiology, behavior, and neuropsychiatric disease. 5-HT mediates its actions via ionotropic and metabotropic 5-HT receptors. The 5-HT(1A) receptor is a metabotropic G protein-coupled receptor linked to the G(i/o) signal...

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Detalhes bibliográficos
Main Authors: Oh, Eugene, Maejima, Takashi, Liu, Chen, Deneris, Evan, Herlitze, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945576/
https://ncbi.nlm.nih.gov/pubmed/20643652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.147298
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