The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents

1. In this study in vitro and in vivo approaches were combined in order to investigate if the anti-epileptic mechanism(s) of action of levetiracetam (LEV; Keppra®) may involve modulation of inhibitory neurotransmission. 2. GABA- and glycine-gated currents were studied in vitro using whole-cell patch...

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Détails bibliographiques
Auteurs principaux: Rigo, J-M, Hans, G, Nguyen, L, Rocher, V, Belachew, S, Malgrange, B, Leprince, P, Moonen, G, Selak, I, Matagne, A, Klitgaard, H
Format: Artigo
Langue:Inglês
Publié: 2002
Sujets:
Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573396/
https://ncbi.nlm.nih.gov/pubmed/12086975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704766
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