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Effects of a phosphodiesterase IV inhibitor rolipram on microsphere embolism-induced defects in memory function and cerebral cyclic AMP signal transduction system in rats

1. The effects of treatment with rolipram, a specific phosphodiesterase IV inhibitor, on learning and memory function and on the cyclic AMP/PKA/CREB signal transduction system were examined in rats with microsphere embolism (ME)-induced cerebral ischaemia. 2. Sustained cerebral ischaemia was induced...

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Bibliografiske detaljer
Main Authors: Nagakura, Akira, Niimura, Makiko, Takeo, Satoshi
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573294/
https://ncbi.nlm.nih.gov/pubmed/11934820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704629
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