Nociceptin/orphanin FQ inhibits capsaicin-induced guinea-pig airway contraction through an inward-rectifier potassium channel

1. Nociceptin/orphanin FQ (N/OFQ), an endogenous opioid-like orphan receptor (NOP receptor, previously termed ORL1 receptor) agonist, has been found to inhibit capsaicin-induced bronchoconstriction in isolated guinea-pig lungs and in vivo. The underlying mechanisms are not clear. In the present stud...

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Autores principales: Jia, Yanlin, Wang, Xin, Aponte, Sonia I, Rivelli, Maria A, Yang, Richard, Rizzo, Charles A, Corboz, Michel R, Priestley, Tony, Hey, John A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573179/
https://ncbi.nlm.nih.gov/pubmed/11834624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704515
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