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Effects of cardioselective K(ATP) channel antagonism on basal, stimulated, and ischaemic myocardial function in in vivo failing canine heart
1. Inhibition of cardiomyocyte-specific ATP-sensitive potassium (K(ATP)) channels prolongs the action potential during intense ischaemia with attendant antiarrhythmic effects. However, this is accompanied by contractile depression in some models. These changes may be particularly troublesome in dila...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2002
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573174/ https://ncbi.nlm.nih.gov/pubmed/11834613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704510 |
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