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ATP sensitive K(+) channels are critical for maintaining myocardial perfusion and high energy phosphates in the failing heart
Congestive heart failure (CHF) is associated with intrinsic alterations of mitochondrial oxidative phosphorylation which lead to increased myocardial cytosolic free ADP. ATP sensitive K(+) channels (K(ATP)) act as metabolic sensors that are important for maintaining coronary blood flow (MBF) and in...
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Publicado no: | J Mol Cell Cardiol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4789110/ https://ncbi.nlm.nih.gov/pubmed/26854629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.02.005 |
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