A study of P2X(1) receptor function in murine megakaryocytes and human platelets reveals synergy with P2Y receptors

1. We have examined the role of ATP-dependent P2X(1) receptors in megakaryocytes (MKs) and platelets using receptor-deficient mice and selective agonists. 2. α,β-meATP- and ATP- evoked ionotropic inward currents were absent in whole-cell recordings from MKs of P2X(1)(−/−) mice, demonstrating that th...

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Hlavní autoři: Vial, Catherine, Rolf, Michael G, Mahaut-Smith, Martyn P, Evans, Richard J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
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Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573149/
https://ncbi.nlm.nih.gov/pubmed/11815371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704486
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