טוען...
Role of the histidine residue at position 105 in the human α5 containing GABA(A) receptor on the affinity and efficacy of benzodiazepine site ligands
1. A histidine residue in the N-terminal extracellular region of α1,2,3,5 subunits of the human GABA(A) receptor, which is replaced by an arginine in α4 and α6 subunits, is a major determinant for high affinity binding of classical benzodiazepine (BZ)-site ligands. The effect of mutating this histid...
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| Main Authors: | , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573121/ https://ncbi.nlm.nih.gov/pubmed/11786501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704459 |
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