Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window

1. The efficacy of the free radical trapping agent NXY-059 in reducing the infarct volume following both transient and permanent focal ischaemia has been examined in rats. 2. In the transient ischaemia model, rats were subjected to a 2 h occlusion of the middle cerebral artery (MCA). Intravenous inf...

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Bibliografiske detaljer
Main Authors: Sydserff, S G, Borelli, A R, Green, A R, Cross, A J
Format: Artigo
Sprog:Inglês
Udgivet: 2002
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573113/
https://ncbi.nlm.nih.gov/pubmed/11786485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704449
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