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Anti-inflammatory effect of synthetic somatostatin analogues in the rat

1. Somatostatin (6.11 nmol kg(−1) i.p.) inhibited neurogenic plasma extravasation evoked by 1% mustard oil and non-neurogenic oedema induced by 5% dextran in the rat skin. 2. Cyclic synthetic octapeptide (TT-248 and TT-250) and heptapeptide (TT-232) somatostatin analogues proved to be more effective...

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Autores principales: Helyes, Zsuzsanna, Pintér, Erika, Németh, József, Kéri, György, Thán, Márta, Oroszi, Gábor, Horváth, Anikó, Szolcsányi, János
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573085/
https://ncbi.nlm.nih.gov/pubmed/11724765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704396
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