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Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO

1. Adenosine produced a biphasic lowering of the mean BP with a drastic bradycardic effect at the highest doses. The first phase hypotensive response was significantly reduced by the nitric oxide (NO) synthase inhibitor L-NAME. 2. The A(2a)/A(2b) agonist NECA produced hypotensive and bradycardic res...

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Autori principali: Nieri, P, Martinotti, E, Calderone, V, Breschi, M C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572997/
https://ncbi.nlm.nih.gov/pubmed/11606314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704301
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