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Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO
1. Adenosine produced a biphasic lowering of the mean BP with a drastic bradycardic effect at the highest doses. The first phase hypotensive response was significantly reduced by the nitric oxide (NO) synthase inhibitor L-NAME. 2. The A(2a)/A(2b) agonist NECA produced hypotensive and bradycardic res...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572997/ https://ncbi.nlm.nih.gov/pubmed/11606314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704301 |
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