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Changes in extracellular pH and myocardial ischaemia alter the cardiac effects of diadenosine tetraphosphate and pentaphosphate

1. The structural conformation of diadenosine tetraphosphate (Ap(4)A) and pentaphosphate (Ap(5)A) has been reported to alter as pH is reduced. As such, it is possible that the cardiac effects of Ap(4)A and Ap(5)A vary during acidosis and myocardial ischaemia due to changes in ligand structure, recep...

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Hlavní autoři: Stavrou, Brigitte M, Beck, Caroline, Flores, Nicholas A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572982/
https://ncbi.nlm.nih.gov/pubmed/11588119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704288
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