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Changes in extracellular pH and myocardial ischaemia alter the cardiac effects of diadenosine tetraphosphate and pentaphosphate

1. The structural conformation of diadenosine tetraphosphate (Ap(4)A) and pentaphosphate (Ap(5)A) has been reported to alter as pH is reduced. As such, it is possible that the cardiac effects of Ap(4)A and Ap(5)A vary during acidosis and myocardial ischaemia due to changes in ligand structure, recep...

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Detalhes bibliográficos
Main Authors: Stavrou, Brigitte M, Beck, Caroline, Flores, Nicholas A
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572982/
https://ncbi.nlm.nih.gov/pubmed/11588119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704288
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