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Hydrogen peroxide-mediated inhibition of lipopolysaccharide-stimulated inhibitory kappa B kinase activity in rat aortic smooth muscle cells

1. In rat aortic smooth muscle cells (RASMC), exposure to lipopolysaccharide (LPS) resulted in NF-κB-DNA binding, degradation of IκB-α, -β and -ε and increased activity of both α and β isoforms of inhibitory kappa B kinase (IKK). 2. Expression of dominant-negative (DN)-IKK-α, IKK-β and NF-κB-inducin...

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Autors principals: Torrie, Lindsay J, MacKenzie, Christopher J, Paul, Andrew, Plevin, Robin
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572956/
https://ncbi.nlm.nih.gov/pubmed/11564658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704259
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