Cibenzoline, an ATP-sensitive K(+) channel blocker, binds to the K(+)-binding site from the cytoplasmic side of gastric H(+),K(+)-ATPase

1. Cibenzoline, (±)-2-(2,2-diphenylcyclopropyl-2-imidazoline succinate, has been clinically used as one of the Class I type antiarrhythmic agents and also reported to block ATP-sensitive K(+) channels in excised membranes from heart and pancreatic β cells. In the present study, we investigated if th...

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Bibliographic Details
Main Authors:	Tabuchi, Yoshiaki, Yashiro, Hiroaki, Hoshina, Satomi, Asano, Shinji, Takeguchi, Noriaki
Format:	Artigo
Language:	Inglês
Published:	2001
Subjects:	Papers
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1572902/ https://ncbi.nlm.nih.gov/pubmed/11739241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704422
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Cibenzoline, an ATP-sensitive K(+) channel blocker, binds to the K(+)-binding site from the cytoplasmic side of gastric H(+),K(+)-ATPase

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