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Antianginal effects of hydroxyfasudil, a Rho-kinase inhibitor, in a canine model of effort angina

1. The effects of Rho-kinase inhibitor, fasudil, and of a more specific Rho-kinase inhibitor, hydroxyfasudil, on pacing-induced myocardial ischaemia were determined in anaesthetized open-chest dogs. 2. The dogs were subjected to left anterior descending coronary artery (LAD) stenosis producing a suf...

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Autors principals: Utsunomiya, T, Satoh, S, Ikegaki, I, Toshima, Y, Asano, T, Shimokawa, H
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572897/
https://ncbi.nlm.nih.gov/pubmed/11739249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704410
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