Saint John's wort: An in vitro analysis of P-glycoprotein induction due to extended exposure

1. Chronic use of Saint John's wort (SJW) has been shown to lower the bioavailability for a variety of co-administered drugs including indinavir, cyclosporin, and digoxin. Decreases in intestinal absorption through induction of the multidrug resistance transporter, P-glycoprotein (P-gp), may ex...

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Hlavní autoři: Perloff, Michael D, von Moltke, Lisa L, Störmer, Elke, Shader, Richard I, Greenblatt, David J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
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Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572891/
https://ncbi.nlm.nih.gov/pubmed/11739235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704399
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