St John's Wort increases expression of P-glycoprotein: Implications for drug interactions

AIMS: St John's Wort (SJW) is widely used in the treatment of depression but concerns have been raised about its potential to interact with other drugs. Co-administration with SJW has resulted in significant reductions in trough plasma concentrations of indinavir and cyclosporin [1, 2]. Inducti...

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Detalhes bibliográficos
Main Authors: Hennessy, M, Kelleher, D, Spiers, J P, Barry, M, Kavanagh, P, Back, D, Mulcahy, F, Feely, J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Drug Disposition
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874544/
https://ncbi.nlm.nih.gov/pubmed/11849198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01516.x
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