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Voltage-dependent acceleration of Ca(v)1.2 channel current decay by (+)- and (−)-isradipine

1. Inhibition of Ca(v)1.2 by antagonist 1,4 dihydropyridines (DHPs) is associated with a drug-induced acceleration of the calcium (Ca(2+)) channel current decay. This feature is contradictorily interpreted as open channel block or as drug-induced inactivation. To elucidate the underlying molecular m...

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Autori principali: Berjukow, S, Hering, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572885/
https://ncbi.nlm.nih.gov/pubmed/11487504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704181
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