Direct effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice

1. The acyl-CoA:cholesterol acyltransferase (ACAT) enzyme is thought to be responsible for foam cell formation and the subsequent progression of atherosclerosis. The apolipoprotein E and low density lipoprotein receptor double knockout (apoE/LDLr-DKO) mouse is an animal model that develops severe hy...

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Détails bibliographiques
Auteurs principaux: Chiwata, Tsuyoshi, Aragane, Katsumi, Fujinami, Koji, Kojima, Kazuhiro, Ishibashi, Shun, Yamada, Nobuhiro, Kusunoki, Jun
Format: Artigo
Langue:Inglês
Publié: 2001
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Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572866/
https://ncbi.nlm.nih.gov/pubmed/11487509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704160
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