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Inhibition of DNA synthesis in cultured hepatocytes by endotoxin-conditioned medium of activated stellate cells is transforming growth factor-β and nitric oxide-independent

1. Activated hepatic stellate cells play a major role in the pathophysiology of chronic liver disease. They can influence the metabolism of hepatocytes by producing a variety of cytokines and growth factors. Upon stimulation with endotoxin, stellate cells also synthesize nitric oxide (NO), a potent...

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Detalhes bibliográficos
Main Authors: Uemura, Tadahiro, Gandhi, Chandrashekhar R
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572860/
https://ncbi.nlm.nih.gov/pubmed/11487524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704151
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