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Prevention of cultured rat stellate cell transformation and endothelin-B receptor upregulation by retinoic acid

1. Physiologically, perisinusoidal hepatic stellate cells (HSC) are quiescent and store retinoids. During liver injury and in cell culture, HSC transform into proliferating myofibroblast-like cells that express α-smooth muscle actin (α-sma) and produce excessive amounts of extracellular matrix. Duri...

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Detalhes bibliográficos
Main Authors: Chi, Xuedong, Anselmi, Kristin, Watkins, Simon, Gandhi, Chandrashekhar R
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573899/
https://ncbi.nlm.nih.gov/pubmed/12813000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705303
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