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A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brain

1. Using a rat model which allows serial blood sampling and concurrent brain microdialysis sampling, we have investigated the temporal kinetic inter-relationship of levetiracetam in serum and brain extracellular fluid (frontal cortex and hippocampus) following systemic administration of levetiraceta...

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Main Authors: Tong, X, Patsalos, P N
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572849/
https://ncbi.nlm.nih.gov/pubmed/11454660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704141
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