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Comparison of serum, cerebrospinal fluid and brain extracellular fluid pharmacokinetics of lamotrigine
1. We investigated the rate of penetration into and the intra-relationship between the serum, cerebrospinal fluid (CSF) and regional brain extracellular fluid (bECF) compartments following systemic administration of lamotrigine in rat. 2. The serum pharmacokinetics were biphasic with an initial dist...
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| Hoofdauteurs: | , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2000
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572088/ https://ncbi.nlm.nih.gov/pubmed/10807660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703337 |
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