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Evidence that ET-1, but not ET-3 and S6b, ET(A)-receptor mediated contractions in isolated rat mesenteric arteries are modulated by co-activation of ET(B) receptors

1. The effects of agonists with endothelin (ET) ET(A)-receptor activity have been analysed in relation to their interaction with ET(B) receptors in rat mesenteric arteries. 2. ET-1, sarafotoxin 6b (S6b) and ET-3 induced large, slow-onset and sustained contractions whereas S6c induced weak transient...

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Detalhes bibliográficos
Main Authors: Adner, Mikael, Shankley, Nigel, Edvinsson, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572843/
https://ncbi.nlm.nih.gov/pubmed/11454667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704135
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