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Effect of cyclosporin A and its vehicle on cardiac and skeletal muscle mitochondria: relationship to efficacy of the respiratory chain

1. Although cyclosporin (CsA) is considered to be the best immunosuppressive molecule in transplantation, it has been suspected to alter mitochondrial respiration of various tissues. 2. We evaluated the acute effect of CsA and its vehicle on maximal oxidative capacity (V(max)) of cardiac, soleus and...

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Autors principals: Sanchez, H, Zoll, J, Bigard, X, Veksler, V, Mettauer, B, Lampert, E, Lonsdorfer, J, Ventura-Clapier, R
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572839/
https://ncbi.nlm.nih.gov/pubmed/11454650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704129
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