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Role of protein kinase C in the reduction of infarct size by N-methyl-1-deoxynojirimycin, an α-1,6-glucosidase inhibitor

1. Preischaemic treatment with N-methyl-1-deoxynojirimycin (MOR-14), an α-1,6-glucosidase inhibitor, attenuates glycogenolysis and lactate accumulation during ischaemia and markedly reduces infarct size in rabbit hearts. In the present study, we have investigated whether protein kinase C (PKC), a pr...

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Detalhes bibliográficos
Main Authors: Arai, Masazumi, Minatoguchi, Shinya, Kumada, Hirokazu, Uno, Yoshihiro, Nishida, Yoshio, Hashimoto, Kazuaki, Wang, Ningyuan, Takemura, Genzou, Fujiwara, Takako, Higashioka, Masaya, Kuwano, Keiichi, Fujiwara, Hisayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572825/
https://ncbi.nlm.nih.gov/pubmed/11429386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704107
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