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Effects of pH on the inhibition of fatty acid amidohydrolase by ibuprofen
1. The pharmacological properties of fatty acid amidohydrolase (FAAH) at different assay pH values were investigated using [(3)H]-anandamide ([(3)H]-AEA) as substrate in rat brain homogenates and in COS-7 cells transfected with wild type and mutant FAAH. 2. Rat brain hydrolysis of [(3)H]-AEA showed...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2001
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572815/ https://ncbi.nlm.nih.gov/pubmed/11399668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704113 |
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