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Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity

1. The cleavage of haeme by haeme oxygenase (HO) yields carbon monoxide (CO), a biologically active molecule which exerts most of its effects via activation of soluble guanylate cyclase (sGC). In the present study, we tested the hypothesis that endogenous CO could modulate inflammatory hyperalgesia....

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Detalhes bibliográficos
Main Authors: Steiner, A A, Branco, L G S, Cunha, F Q, Ferreira, S H
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572732/
https://ncbi.nlm.nih.gov/pubmed/11309238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704014
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