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Role of the haeme oxygenase/carbon monoxide pathway in mechanical nociceptor hypersensitivity

1. The cleavage of haeme by haeme oxygenase (HO) yields carbon monoxide (CO), a biologically active molecule which exerts most of its effects via activation of soluble guanylate cyclase (sGC). In the present study, we tested the hypothesis that endogenous CO could modulate inflammatory hyperalgesia....

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Autors principals: Steiner, A A, Branco, L G S, Cunha, F Q, Ferreira, S H
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572732/
https://ncbi.nlm.nih.gov/pubmed/11309238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704014
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