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Long-lasting antinociceptive effects of a novel dynorphin analogue, Tyr-D-Ala-Phe-Leu-Arg ψ (CH(2)NH) Arg-NH(2), in mice
1. Tyr-D-Ala-Phe-Leu-Arg ψ (CH(2)NH) Arg-NH(2) (SK-9709) is a dynorphin derivative in which the peptide bond was replaced with a ψ (CH(2)NH) bond. In the present study, the antinociceptive effects of SK-9709 were determined in an acetic acid-induced writhing test and a hot-plate test. 2. In the acet...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572722/ https://ncbi.nlm.nih.gov/pubmed/11309268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703982 |
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