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Chronic vascular toxicity of doxorubicin in an organ-cultured artery

1. We investigated the chronic effects of doxorubicin (DXR) on morphological and functional changes in the rabbit mesenteric artery using an organ culture system. 2. In arteries cultured with 0.3 μM DXR for 7 days, the contractions induced by noradrenaline, but not those induced by endothelin-1 or h...

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Detalhes bibliográficos
Main Authors: Murata, Takahisa, Yamawaki, Hideyuki, Hori, Masatoshi, Sato, Koichi, Ozaki, Hiroshi, Karaki, Hideaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572694/
https://ncbi.nlm.nih.gov/pubmed/11264228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703959
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