[(125)I]-(Pyr(1))Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man

1. We have determined the binding characteristics of [(125)I]-(Pyr(1))Apelin-13, a putative ligand for the APJ orphan receptor in human cardiovascular and rat tissue and investigated the functional properties of (Pyr(1))Apelin-13 in human saphenous vein. 2. The binding of [(125)I]-(Pyr(1))Apelin-13...

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Bibliografiske detaljer
Main Authors: Katugampola, Sidath D, Maguire, Janet J, Matthewson, Stewart R, Davenport, Anthony P
Format: Artigo
Sprog:Inglês
Udgivet: 2001
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Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572672/
https://ncbi.nlm.nih.gov/pubmed/11250876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703939
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