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Involvement of cyclic AMP systems in morphine physical dependence in mice: prevention of development of morphine dependence by rolipram, a phosphodiesterase 4 inhibitor
1. In this study, we examined whether morphine dependence was inhibited by rolipram, a cyclic AMP selective phosphodiesterase inhibitor in mice, since a role for the cyclic AMP systems in the development of morphine dependence has been reported. 2. Mice, which received morphine (10 mg kg(−1) s.c.) t...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572651/ https://ncbi.nlm.nih.gov/pubmed/11226142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703912 |
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