The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release

Tissue plasminogen activator (tPA) is a serine protease that catalyzes the conversion of plasminogen (plg) to plasmin, which in turn functions to degrade extracellular matrix proteins in the central nervous system. The tPA-plasmin system plays a role in synaptic plasticity and remodeling. Here we sh...

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Detalhes bibliográficos
Main Authors: Nagai, Taku, Yamada, Kiyofumi, Yoshimura, Masako, Ishikawa, Kazuhiro, Miyamoto, Yoshiaki, Hashimoto, Kazuki, Noda, Yukihiro, Nitta, Atsumi, Nabeshima, Toshitaka
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC373517/
https://ncbi.nlm.nih.gov/pubmed/14988509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306587101
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