The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release

Tissue plasminogen activator (tPA) is a serine protease that catalyzes the conversion of plasminogen (plg) to plasmin, which in turn functions to degrade extracellular matrix proteins in the central nervous system. The tPA-plasmin system plays a role in synaptic plasticity and remodeling. Here we sh...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Nagai, Taku, Yamada, Kiyofumi, Yoshimura, Masako, Ishikawa, Kazuhiro, Miyamoto, Yoshiaki, Hashimoto, Kazuki, Noda, Yukihiro, Nitta, Atsumi, Nabeshima, Toshitaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
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Biological Sciences
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14988509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0306587101
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